Laboratory

Description: Carousel lid 820 mm Ø Height 595 - 780 mm Diameter of rollers 610 mm Dry weight (including accessories) 60 kg Wax baths 2 (3 optional) Wax baths capacity 1.8 Liters Wax baths temperature range 45 °C - 65 ° Standard tissue basket capacity max 100 cassettes Nominal voltage 100/120/230/240 V AC ± 10% Nominal frequency 50/60 Hz Excess temperature cutout 75 °C ± 4 °C Reagent containers 10 (9) Reagent container capacity 1.8 liters Standard tissue baskets 1 (2 optional) Programs 9, freely selectable Programmable infiltration time per station 99 h 59 min Delayed start 9 days Drain time 60 s Vacuum device pressure difference max 500 hPa (approx. 0.5 bar)

Description: HistoCore PEARL is a compact instrument with a small footprint to maximize your laboratory space. It also provides the essential features needed for added safety, efficient tissue processing and optimized workflows. Intuitive New Technology The xylene-resistant touchscreen, with multilingual intuitive interface, guides the technician smoothly through the processing programs to reduce errors. Log files can be quickly downloaded via USB connection to help maintain accurate records. Optimized Fume Protection Fully enclosed tissue processing protects the lab and your staff by reducing exposure to hazardous fumes. HistoCore PEARL provides triple fume protection with extraction at the retort, an external exhaust adapter, and an activated carbon filter. Added safety for your staff! Simple Operation and Maintenance The drawer style design for paraffin baths allows for easy filling and draining. Additional trays under the paraffin baths and reagent bottles effectively collect spilled liquids and chemicals to provide user safety.

Description: Dimensions (W x D x H): 804 x 715 x 1533 mm Weight (Instrument Only) : 235 kg Weight (Including Reagents) : 315 kg Number of reagent containers 17 reagent bottles, 1 condensate bottle Maximum bottle volume : Max. 3.88 L Number of paraffin baths : 4 Capacity : Max. 3.9 L per paraffin bath Melting time : max. 7 hours an ambient temperature of 23°C-25°C Temperature settings range : Paraffin Melting Point setting: 50°C-65°C Standby temperature setting : Paraffin Melting Point +2°C and max. 71°C Capacity : max. 2x200 cassettes Temperature (paraffin) : Paraffin temperature selectable from 58°C to 77°C Temperature (processing reagents) : Ambient temperature or 35°C-65°C Temperature (cleaning reagents) : 35°C -85°C Filling vacuum : -60 kPa Draining pressure : 45 kPa

Description: Improve quality, reduce errors, and save time with dedicated plug and play consumables. From glass slides and coverslips to wax and bulk reagents, smooth running of any laboratory depends on a consistent supply of high-quality consumables Cassettes, Slides, Coverglass, Paraffins, Microtome, Cryostat Blades, Routine (H&E), Special Stains, Reagents, Solutions, Archiving, Transport, Storage, Mounting Media, Adhesives, Ancillaries

Description: Dimensions (W x D x H): 438 mm x 472 mm x 265 mm (17.24 x 18.58 x 10.43 in) Weight (without accessories): 29 kg (63.9 lbs) Section thickness setting range: 0.5 - 60 µm Total horizontal specimen feed: 25 mm Vertical specimen stroke: 59 mm Specimen retraction: ON/OFF approx. 20 µm Specimen orientation: XY - ±8° Trimming thickness: 10 µm, 50 µm

Description: Product Specifications General Type: Mechanical Nominal Supply Voltage: N/A Nominal Frequency: N/A Maximum Power Consumption: N/A Protection Class: N/A Power Fuses: N/A Pollution Degree: N/A Overvoltage Category: N/A Maximum Heat Emission: N/A Operating Temperature Range: +18°C to +30°C Temperature Range During Storage: +5°C to +50°C Relative Humidity During Operation: 20% to Max. 80% Non-Condensing Relative Humidity During Storage: 10% to Max. 85% Non-Condensing Dimensions & Weight BASIC INSTRUMENT Width (including handwheel and coarse feed wheel): 477 mm Depth (including waste tray): 620 mm Height (without top tray): 295 mm Weight (without accessories): Approx. 31 kg CONTROL PANEL Type: N/A Width: N/A Depth: N/A Height: N/A Height (in inclined position): N/A Weight (net): N/A Microtome Performance Specs Specimen Feed: approx. 24 mm ±2 mm Vertical Stroke: 70 mm ±1 mm Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm Motorized Sectioning Speeds: N/A SPECIMEN RETRACTION In Manual Sectioning Mode: Approx. 40 µm (can be turned off) In Motorized Sectioning Mode: N/A SPECIMEN ORIENTATION Horizontal: ± 8° Vertical: ± 8° SECTION THICKNESS SETTINGS Range: 1 - 60 µm Setting Values: 1 - 10 µm (in 1 µm increments) 10 - 20 µm (in 2 µm increments) 20 - 60 µm (in 5 µm increments) TRIMMING SECTION THICKNESS SETTINGS: Range: 10 µm, 30 µm Setting Values: N/A Additional Specifications Handwheel Balance System: Handwheel Lock / Brake: 2 Mechanical Locks Safety Hand Wheel: N/A Coarse Feed Wheel Turn Direction: User-Selectable - Clockwise or Counter-Clockwise WASTE TRAY Type Anti-static Waste Tray Volume 1400 ml SELECTABLE CUTTING MODES Rock Mode: - manual Single Mode: Continuous Mode: Step Mode: Program Mode: BLADE HOLDER Type: 2-in 1 for high and low profile blades North-South Movement: ± 24 mm East-West Movement: N/A Lateral Displacement Function: via knife holder CE clamping top SPECIAL FEATURES Remaining Feed Indicator Visual Section Counter Section Thickness Totalizer Memory Position Special Spindle for Precise Semi-Thin Sectioning Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning Precise 3D Object Head Stop Position

Description: Product Specifications General Type: Semi-Motorized Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC Nominal Frequency: 50/60 Hz Maximum Power Consumption: 40 VA Protection Class: I Power Fuses: 2 x T1.0 AL, 250V Pollution Degree: 2 Overvoltage Category: II Maximum Heat Emission: 70 J/s Operating Temperature Range: +18°C to +30°C Temperature Range During Storage: +5°C to +50°C Relative Humidity During Operation: 20% to Max. 80% Non-Condensing Relative Humidity During Storage: 10% to Max. 85% Non-Condensing Dimensions & Weight BASIC INSTRUMENT Width (including handwheel and coarse feed wheel): 477 mm Depth (including waste tray): 620 mm Height (without top tray): 295 mm Weight (without accessories): Approx. 31 kg CONTROL PANEL Type: Separate control panel & in-housing integrated instrument control panel Width: 94 mm Depth: 193 mm Height: 50 mm Height (in inclined position): 81 mm Weight (net): 0.5 kg Microtome Performance Specs Specimen Feed: approx. 24 mm ±1 mm Vertical Stroke: 70 mm ±1 mm Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm Motorized Sectioning Speeds: N/A SPECIMEN RETRACTION In Manual Sectioning Mode: 5 - 100 µm (in 5 µm increments); can be turned off In Motorized Sectioning Mode: N/A SPECIMEN ORIENTATION Horizontal: ± 8° Vertical: ± 8° SECTION THICKNESS SETTINGS Range: 0.5 - 100 µm Setting Values: 0.5 - 5 µm (in 0.5 µm increments) 5 - 20 µm (in 1 µm increments) 20 - 60 µm (in 5 µm increments) 60 - 100 µm (in 10 µm increments) TRIMMING SECTION THICKNESS SETTINGS: Range: 1 - 600 µm Setting Values: 1 - 10 µm (in 1 µm increments) 10 - 20 µm (in 2 µm increments) 20 - 50 µm (in 5 µm increments) 50 - 100 µm (in 10 µm increments) 100 - 600 µm (in 50 µm increments) Additional Specifications Handwheel Balance System: Handwheel Lock / Brake: 2 Mechanical Locks Safety Hand Wheel: N/A Coarse Feed Wheel Turn Direction: User-Selectable - Clockwise or Counter-Clockwise WASTE TRAY Type Anti-static Waste Tray Volume 1400 ml SELECTABLE CUTTING MODES Rock Mode: - with activated retraction Single Mode: Continuous Mode: Step Mode: Program Mode: BLADE HOLDER Type: 2-in 1 for high and low profile blades North-South Movement: ± 24 mm East-West Movement: 3 Positions Lateral Displacement Function: via knife holder CE clamping top SPECIAL FEATURES Remaining Feed Indicator Visual and Acoustical Section Counter Section Thickness Totalizer Memory Position Special Spindle for Precise Semi-Thin Sectioning Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning Precise 3D Object Head Stop Position

Description: Product Specifications General Type: Motorized Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC Nominal Frequency: 50/60 Hz Maximum Power Consumption: 100 VA Protection Class: I Power Fuses: 2 x T 3.15 AL, 250V Pollution Degree: 2 Overvoltage Category: II Maximum Heat Emission: 340 J/s Operating Temperature Range: +18°C to +35°C Temperature Range During Storage: +5°C to +50°C Relative Humidity During Operation: 20% to Max. 80% Non-Condensing Relative Humidity During Storage: 10% to Max. 85% Non-Condensing Dimensions & Weight BASIC INSTRUMENT Width (including handwheel and coarse feed wheel): 477 mm Depth (including waste tray): 620 mm Height (without top tray): 295 mm Weight (without accessories): Approx. 40 kg CONTROL PANEL Type: Separate control panel & in-housing integrated instrument control panel Width: 119 mm Depth: 193 mm Height: 50 mm Height (in inclined position): 81 mm Weight (net): 0.6 kg Microtome Performance Specs Specimen Feed: approx. 24 mm ±1 mm Vertical Stroke: 70 mm ±1 mm Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm Motorized Sectioning Speeds: 0 - 420 mm/s ±10% SPECIMEN RETRACTION In Manual Sectioning Mode: 5 - 100 µm (in 5 µm increments); can be turned off In Motorized Sectioning Mode: Speed-Dependent; can be turned off SPECIMEN ORIENTATION Horizontal: ± 8° Vertical: ± 8° SECTION THICKNESS SETTINGS Range: 0.5 - 100 µm Setting Values: 0.5 - 5 µm (in 0.5 µm increments) 5 - 20 µm (in 1 µm increments) 20 - 60 µm (in 5 µm increments) 60 - 100 µm (in 10 µm increments) TRIMMING SECTION THICKNESS SETTINGS: Range: 1 - 600 µm Setting Values: 1 - 10 µm (in 1 µm increments) 10 - 20 µm (in 2 µm increments) 20 - 50 µm (in 5 µm increments) 50 - 100 µm (in 10 µm increments) 100 - 600 µm (in 50 µm increments) Additional Specifications Handwheel Balance System: Handwheel Lock / Brake: 2 Mechanical Locks, 1 Electronic Brake Safety Hand Wheel: Handle can be Centered Coarse Feed Wheel Turn Direction: Clockwise or Counter-Clockwise WASTE TRAY Type: Anti-static Waste Tray Volume: 1400 ml SELECTABLE CUTTING MODES Rock Mode: - with activated retraction Single Mode: Continuous Mode: Step Mode: Program Mode: BLADE HOLDER Type: 2-in 1 for high and low profile blades North-South Movement: ± 24 mm East-West Movement: 3 Positions Lateral Displacement Function: via knife holder CE clamping top SPECIAL FEATURES Remaining Feed Indicator: Visual and Acoustical Section Counter: Section Thickness Totalizer: Memory Position: Special Spindle for Precise Semi-Thin Sectioning: Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning: Precise 3D Object Head Stop Position:

Description: Technical Specifications HistoCore Arcadia Hot plate - Heated Paraffin Embedding Station GENERAL Dimensions (W x D x H): 636 mm x 560 mm x 384 mm Weight: 27 kg Operating temperatures: 50°C to 75°C Removable tray: approx. 150 cassettes Paraffin tank: max 4 L Environmental operating temperature: 20°C to + 30°C Power supply: 110 - 120 V AC, 220 - 240 V AC, 50/60 Hz Overvoltage Category: II Power consumption: 1000 VA max HistoCore Arcadia Cold - Cold Plate GENERAL Dimensions (D x W x H): 636 mm x 400 mm x 384 mm Weight: 32 kg Operating temperatures: -6°C (self-regulating) Maximum Power Consumption: 100 VA Min. guaranteed workload capacity: 65 blocks solidified in 30 minutes Environmental operating temperature: 20°C to +30 °C Power supply: 100V/110 - 120V AC/220 - 240 V AC, 50/60 Hz Power consumption: 400 VA max

Description: DB80 LX: Low-profile disposable microtome blade with a special coating recommended for a wide range of tissue types from routine biopsies to dense and harder tissues. DB80 LS: Low-profile disposable microtome blade recommended for routine soft tissue and thin sectioning. DB80 HS: High-profile disposable microtome blade recommended for all routine specimens in room temperature and cryo-sectioning. 819: Low-profile disposable microtome blade recommended for routine sectioning of FFPE tissue blocks. 818: High-profile disposable microtome blade recommended for all routine specimens in room temperature sectioning.

Description: Product Specifications Dimensions and weight specification Overall size of device in operating mode (Width x Depth x Height, mm): Water bath: 280 x 280 x 105 Slide dryer: 200 x 280 x 98 Empty weight (without accessories, kg): 3 Overall weight (with accessories, kg): Water Bath: 3 kg Slide Dryer: 3 Kg Device weight including packaging (kg): 4

Description: Product Specifications Mechanical & Electrical Specifications Instrument Dimensions (W x D x H): 200 x 280 x 98 mm Overall size serial packaging (Width x Depth x Height): 415 x 395 x 215 mm Performance & Features Temperature: Up to 75℃ Angles of heating plate: 45° Slide rack capacity: 30 slides

Description: Product Features Barcode printed slide Barcode-printed slides used for tracking support the reduction of human error through automation and traceability. Ink-jet technology The Leica IP S slide printer uses a resistant ink that prevails against the chemicals used in your histology laboratory. The imprint on each slide remains readily identifiable throughout the histology process and storage period. Batch job printing Batch job printing: 4 sec. per slide (two-line printing). Single-slide printing: 10 sec. per slide; for high throughput and optimized workflow. Automated unload station The optional unload station holds up to 110 slides, automating the manual slide sorting process and helping to avoid sequence mix up of printed slides. LIS integration Designed to be used as a centralized single-user, or multiple-user PC workstation, where several printers can be connected to one PC.

Description: Product Features Printing Quality Sharp print capability enhances the slide readability and minimizes specimen misidentification. Intuitive Technology for More Control Easy printer operation with label design software helps maintain lab efficiency. Connect your printer to a PC to avoid transcribing data and handwritten labels. Validated PERMASLIDE Slides Leica Biosystems recommends the use of PERMASLIDE slides, validated for the HistoCore PERMA S slide printer. The slides are available in white with clipped corners, non-adhesive (PERMASLIDE) and adhesive option (PERMASLIDE Plus), and provide consistent print results. Easy-to-load Slide Cartridge The 100-slide cartridge capacity allows for an easy and quick exchange of additional slides. Optional extra cartridges can be used to store and load a variety of slide types.